Table of Contents
What does verigene test for?
The VERIGENE® Gram-Positive Blood Culture Nucleic Acid Test (BC-GP) performed using the sample-to-result VERIGENE System is a qualitative, multiplexed in vitro diagnostic test for the simultaneous detection and identification of potentially pathogenic gram-positive bacteria which may cause bloodstream infection (BSI).
What is Gram-positive blood culture?
Many Gram-positive bacilli are part of the normal skin flora thereby able to contaminate blood cultures or colonize intravenous catheters. Identifying these organisms in a blood culture may be suggestive of false-positive results. They include Propionibacterium acnes, Corynebacterium species and Bacillus species.
How long does Verigene take?
While conventional microbiological methods may require 2 to 4 days to produce bacterial identification and susceptibility results, Verigene BC-GP provides results within 2.5 hours of blood culture positivity.
How does Verigene work?
The VERIGENE System instrumentation consists of a VERIGENE Reader and one or multiple VERIGENE Processor SPs. The VERIGENE Reader manages sample information, reads results from processed cartridges, and allows for result printing, internal data storage, and LIS connectivity without the need for an external PC.
How long does it take for results on blood culture?
You may be able to get early results within 24 hours of your blood tests. But you might need to wait 48 to 72 hours to learn what kind of yeast or bacteria is causing your infection. You might need other tests, too. You may be able to get early results within 24 hours of your blood tests.
How does accelerate pheno work?
The Accelerate Pheno system uses automated fluorescence in situ hybridization technology with morphokinetic cellular analysis to provide rapid species identification (ID) and antimicrobial susceptibility testing (AST) results for the most commonly identified organisms in bloodstream infections.
How serious is a positive blood culture?
If the blood culture is positive, this means you have a bacterial or yeast infection in your blood. The results usually help your doctor identify the specific bacteria or fungi that’s causing the infection.
What diseases are caused by Gram-positive bacteria?
Gram-positive infections include methicillin-resistant Staphylococcus aureus (MRSA), strep infections, and toxic shock. Gram-negative infections include salmonella, pneumonia, urinary tract infections, and gonorrhea.
Is verigene a PCR?
NanoGrid Technology in VERIGENE Tests The detection of DNA or RNA targets on the VERIGENE System using NanoGrid Technology entails: Automated nucleic acid extraction and PCR amplification (if necessary) from a clinical sample on the VERIGENE Processor SP.
What is verigene nucleic acid test?
The Verigene® Gram-Positive Blood Culture Nucleic Acid Test (BC-GP) performed using the sample-to- result Verigene System is a qualitative, multiplexed in vitro diagnostic test for the simultaneous detection and identification of potentially pathogenic gram-positive bacteria which may cause bloodstream infection (BSI).
How do you get a gram-positive infection?
Most gram-positive infections are caused by normal resident microflora of the skin, mucous membranes, and gastrointestinal tract. Critically ill hospitalized patients are at increased risk for infections with opportunistic gram-positive bacteria.
How do you treat a positive blood culture?
The tops of the blood culture bottles should also be sterilized with the application of 70% isopropyl alcohol. Disinfecting agents such as iodine tincture, chlorhexidine gluconate, chlorine peroxide are more effective as compared to agents with povidone-iodine.
Does verigene use PCR?
NanoGrid Technology in VERIGENE Tests Automated nucleic acid extraction and PCR amplification (if necessary) from a clinical sample on the VERIGENE Processor SP.
What is Morphokinetic cellular analysis?
Morphokinetic Cellular Analysis is an analytical method that includes digital microscopy to acquire images, as well as machine learning algorithms that analyze individual live cells and the microcolony that they grow into, under a variety of different conditions.
What is a BC kit?
Type of Test: The Accelerate PhenoTest BC kit is a multiplexed in vitro diagnostic test utilizing both qualitative nucleic acid fluorescence in situ hybridization (FISH) identification and quantitative, antimicrobial susceptibility testing (AST) methods and is intended for use with the Accelerate Pheno System.