What is the difference between the brain of a rat and a mouse?

What is the difference between the brain of a rat and a mouse?

The researchers also showed that adult rat brains contain more young neurons than adult mouse brains, and that these cells mature much faster. In addition, more new neurons are activated in rats during memory tasks. These findings could resolve inconsistencies in the literature about rodent neurogenesis.

What is rat hippocampus?

The hippocampal formation is a bilateral structure sandwiched between the cerebral cortex and the thalamus. Figure 1 depicts a reconstruction of the hippocampus (yellow) in its three-dimensional (3D) position within the rat’s brain. These 3D reconstructions were made from the serial sections of LONI’s Rat Brain Atlas.

How similar are rat and human brains?

Even though the rat brain is smaller and less complex than the human brain, research has shown that the two are remarkably similar in structure and function. Both consist of a vast amount of highly connected neurons that are constantly talking to each other.

Which part is major part of brain in rat?

The cerebral and cerebellar hemispheres are attached to a much smaller core or brainstem that is derived from the interbrain, midbrain, and hindbrain vesicles and extends caudally as the spinal cord. The major parts of the adult rat brain are more easily appreciated in a midsagittal or bisected view (fig. 1, bottom).

Why do we study rat brains?

The most important reason for using rats and mice in research is to model aspects of human physiology and function, most notably to advance our understanding of human diseases.

Why do we use rats for brain research?

For decades, scientists have routinely used rats as a main model for brain research. “Its brain is larger than that of a mouse, so it’s easier to study the structures,” said Joyce Peterson, a spokeswoman for the Jackson Laboratory in Bar Harbor, Maine.

Where is the hippocampus in the rat brain?

The hippocampal region comprises the hippocampal formation and the parahippocampal region (Cappaert et al., 2014). The hippocampal formation is a C-shaped structure, positioned posteriorly in the hemisphere of the rat brain (Figs. 1A, A′), bordering on the septal complex dorsally and the amygdaloid complex ventrally.

Where are theta waves generated in the brain?

The hippocampus is the main structure involved in the generation of the 4- to 12-Hz theta (θ) rhythm, which is one of the most regular EEG oscillation that can be recorded from the mammalian brain.

Why are rats used to study the brain?

Although rats do not ‘think’ like humans, some of their brain structure resembles the more primitive elements of human brains, and hence they can be used to model some human behaviours.

Why are rat brains smooth?

However, folded brains are hardly ubiquitous, as most animals’ brains aren’t folded. For instance, the cortex of mice and rats does not expand enough during development to lead to folding, meaning their brains are wholly smooth surfaces.

What are rats used for?

Most of the mice and rats used in medical trials are inbred so they are almost identical genetically helping to make the results of medical trials more uniform. Another reason they’re used as models in medical testing is that their genetic, biological and behavior characteristics closely resemble those of humans.

What is hippocampus function?

Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders.

What is the purpose of rats?

Rats are rodents that do actually serve a purpose in the ecosystem. They are scavengers and opportunistic eaters. They will eat garbage and other things that people throw away. Plus, rats are important as part of the predatory ecosystem.